Every dropout costs an estimated $19,533 to replace.
The cost isn't just from confusion—it's from the job of participating being poorly supported. Replacing a participant costs 3x more than recruiting them. Clear Trials keeps them informed—so staying enrolled feels less like a burden.
Source: Tufts CSDD
The cost of participant confusion
Many report they didn't fully understand what they signed up for.
Source: Rotenstein et al., JAMA 2024; Tufts CSDD
Versus $6,533 to recruit them in the first place.
Source: Tufts CSDD
Protocol amendments mean re-explaining everything. Again.
Sources: Tufts CSDD; protocol amendment benchmarks (Springer/TIRS 2024)
Research links comprehension gaps to retention challenges — and retention challenges to higher costs.
What you get
Plain-language documents
Plain-language versions of your IRB-approved documents. Designed to preserve key information, including risks, without adding promotional content.
Ongoing access
Not just consent day. Every visit. Every amendment.
Caregiver inclusion
The people managing logistics get the same information.
Comprehension signals
Spot comprehension gaps before they become retention risks.
Built for decentralized trials
As trials become more decentralized, participants need accessible information when they can't easily reach site staff.
Remote participant support
Participants can access clear answers from anywhere, reducing the burden on remote site coordinators and improving participant experience.
Consistent experience
Ensure every participant—whether at a traditional site or fully remote—receives the same level of accessible information and support.
Reduced site variability
Standardize participant education across all sites and locations, reducing variability in comprehension and compliance.
How Clear Trials is different
Reminders don't work if participants don't understand them.
Engagement platforms assume comprehension. We help create it. This isn't gamification—it's making sure people understand what they agreed to.
The status quo doesn't scale as trials decentralize.
Manual coordinator support works for 20 participants—not 200. As trials get larger and more decentralized, the old model breaks.
The participant's job isn't modular.
Point solutions—eConsent, reminder apps, resource portals—create fragmentation. One platform addresses the full job of participating.
Measuring value
Clear Trials provides visibility into how participants are using information, helping you demonstrate ROI.
Studies suggest plain-language materials can reduce participant questions
ACRP surveys; digital consent implementation studies
Access to study information
Research links higher comprehension to lower dropout rates
PMC meta-analysis on ICF comprehension
Informed participants may better follow study procedures
Improved comprehension supports protocol adherence