Clinical trial participants deserve more than a 30-page PDF. They deserve clarity.
Clear Trials transforms complex consent forms and protocols into plain language—designed to support participant comprehension and reduce the communication burden on coordinators.
Consent forms average a 10th–14th grade reading level. Only about 12% of U.S. adults read at the “proficient” literacy level (NAAL).
Clear Trials is the only platform purpose-built around the full job of being a clinical trial participant—not just simplifying documents, but supporting comprehension from enrollment through the last visit.
The cost of confusion is staggering.
When participants don't understand their trial, they leave—and the consequences cascade across timelines, budgets, and data quality.
average cost to replace a single dropped participant
higher dropout when participants don't understand consent
of coordinators consider their workload excessive
Sources: $19.5K — Tufts CSDD; 2.2x — PMC meta-analysis on ICF comprehension; 78% — BMC Health Services Research 2025
What the research shows — and what Clear Trials is built to address.
Clear Trials is designed to reduce repetitive participant questions, support comprehension, and remove one of the most common barriers to retention.
What research shows about retention
Published research shows participants with higher trial comprehension are up to 2.2x less likely to withdraw. Clear Trials is built to close that comprehension gap by simplifying consent forms to a 6th–8th grade reading level.
2.2x — PMC meta-analysis on ICF comprehension
Reduce coordinator burden
Coordinators spend 5–8 hours each week answering the same participant questions. Clear Trials gives participants 24/7 access to answers sourced directly from their trial documents.
5–8 hours/week — ACRP industry surveys
Deliver on time and budget
Fewer dropouts mean fewer costly re-recruitments. 80% of sponsors prefer smaller CROs for flexibility—Clear Trials gives you a retention tool that turns your size into an advantage.
80% — Applied Clinical Trials survey
The full job of participating—supported.
Plain-language summaries, timelines, and answers. Participants can share access with family or caregivers—a differentiator that helps support networks stay informed. Designed to preserve key information, including risks, without adding promotional content. Always pointing back to official documents and the study team.
Orient to the study
Plain-language synthesis of consent forms and protocols—understand what you're signing up for
Get answers when they come up
Semantic search across your documents—24/7, sourced from your actual trial materials
Involve your support system
Caregiver access and sharing—the people helping you can see the same information
A coordinator can hand-hold 20 participants. They can't hand-hold 200.
As trials get larger and more decentralized, the old model breaks. Clear Trials is designed to support retention and efficiency from one platform, one implementation—no linear headcount scaling.
Live in weeks, not quarters.
AI guardrails designed in consultation with IRB professionals. Full audit trails. You stay in control.
Unlike generic LLMs, Clear Trials operates within strict, contained boundaries. Every output is editable, includes complete audit trails, and is fully reviewable before participants ever see it.
- Nothing reaches participants without your explicit approval
- Complete audit trails for every document transformation
- HIPAA-compliant infrastructure, no PHI in the application database
- Designed to support ICH-GCP compliance from the ground up
Support comprehension. Reduce coordinator burden. Stand out to sponsors.
See how Clear Trials can work for your organization.