Your coordinators are burning out. Your participants are dropping out.
Support participant engagement and on-protocol adherence—without burning out your coordinators. Clear Trials delivers plain-language trial information that participants can access 24/7—without adding compliance risk.
The numbers behind the problem.
Every dropped participant, every burned-out coordinator, every delayed timeline has a dollar figure attached. Here's what the research shows.
Average cost to replace one dropped participant
Recruiting, screening, and onboarding a replacement participant costs your trial nearly $20K per seat. For a 200-participant study, even a 10% improvement in retention saves nearly $400K in re-recruitment costs alone.
Source: Tufts Center for the Study of Drug Development (CSDD)
Higher dropout when participants don't understand consent
Participants who leave the consent visit without true comprehension are more than twice as likely to drop out. Research suggests that improving understanding at enrollment may help protect retention numbers and trial timelines.
Source: PMC meta-analysis of informed consent comprehension and retention
Of coordinators consider their workload excessive
Coordinator burnout drives turnover, and turnover disrupts continuity of care. Every repetitive question a coordinator fields is time not spent on protocol-critical work. Reducing low-value touchpoints protects your most valuable operational asset.
Source: BMC Health Services Research 2025
What the research shows — and what Clear Trials is designed to address.
Two challenges driving the purchase: supporting participant retention and freeing coordinators from low-value touchpoints.
The retention challenge
Address the confusion, overwhelm, and disengagement that published research links to higher dropout rates. Research shows participants with poor comprehension are up to 2.2x more likely to withdraw; each additional grade level of reading difficulty adds to that risk.
2.2x — PMC meta-analysis. 16% — Health literacy research
The operational efficiency challenge
Reduce low-value coordinator touchpoints—the "when is my next visit?" calls—so coordinators focus on clinical tasks, not logistics. Coordinators spend 5–8 hours each week fielding the same questions; 78% consider their workload excessive.
5–8 hours/week — ACRP industry surveys. 78% — BMC Health Services Research 2025
How participant comprehension drives your KPIs
| What participants get | What your organization gains | How you measure it |
|---|---|---|
| Understand the study | Fewer confusion-driven dropouts | Retention rate, early dropout % |
| Know what's coming next | Fewer missed/rescheduled visits | Visit compliance rate |
| Get answers on demand | Fewer inbound coordinator calls | Call volume per participant |
| Involve my caregiver | Stronger support = better adherence | Caregiver activation rate |
How Clear Trials compares.
Every alternative has a tradeoff. Here's what you need to know.
Status quo
Manual coordinator support doesn't scale. Quantify coordinator hours per participant, cost per dropout, timeline delays—the invisible cost becomes visible as trials grow.
Point solutions
eConsent, reminder apps, resource portals—the participant's job isn't modular. One platform vs. three vendors, three apps, three integrations.
Build it ourselves
The job of a CRO is to run trials, not build participant software. Plain-language synthesis and semantic search against ICFs are hard product problems. Clear Trials can be live in weeks, not quarters.
Simple to integrate. Nothing to disrupt.
Clear Trials fits into your existing workflow. No new systems for coordinators to learn.
Upload documents
Share your IRB-approved consent forms and protocols. We generate plain-language versions using AI guardrails designed in consultation with IRB professionals.
You review and approve
Every simplified document goes through your review. You edit anything you want. Complete audit trails. Nothing reaches participants without your sign-off.
Participants access 24/7
Coordinators provide access codes at enrollment. Participants see their trial information simplified, searchable, and always available from any device.
You see the impact
Aggregate comprehension and engagement metrics across your trials. No individual participant data shared without consent.
What we never do.
Our AI operates within strict, contained boundaries—designed in consultation with IRB professionals. We simplify. We don't spin.
Add claims that aren’t in the source document
Minimize risks or side effects
Use promotional language
Provide medical advice or alter voluntary participation framing
HIPAA-compliant. Designed to support ICH-GCP compliance. No PHI in our application database.
Also built for site networks and sponsors.
If you manage multiple sites or sponsor trials, Clear Trials can standardize how participants access trial information across your portfolio.
- Standardize participant comprehension support across sites
- Aggregate engagement and comprehension metrics across your network
- Support decentralized trials where you can't explain in person
- Offer Clear Trials as a value-added service to your sponsors
See what Clear Trials looks like for your organization.
We're working with a select group of CROs, site networks, and sponsors for our launch. Let's talk about your trials.